Yes, Virginia, There Is an Asthma Gene

OCTOBER 01, 2005

Researchers have discovered a gene that seems to influence susceptibility to asthma. Furthermore, the CYFIP2 protein produced by the gene could serve as a target for new asthma drugs, according to a study reported in the American Journal of Respiratory and Critical Care Medicine (July 15, 2005).

In an earlier study, the researchers connected mapped areas on chromosome 5 in patients with allergic asthma. For the current study, the researchers took the evidence a step beyond by identifying a gene in this region that influences asthma vulnerability. The investigators performed genetic screening in 155 families with asthma. The results showed 6 DNA changes that affect the development of asthma. These mutations were found in a gene for CYFIP2. Further examination suggested that CYFIP2 impacts the risk of asthma by affecting the function of T cells. The investigators said that more testing is needed to explain how changes in these cells may promote asthma.


Become A RESPIMAT T.O.P. Performer 

Get to know RESPIMAT, the slow-moving mist inhaler from Boehringer Ingelheim Pharmaceuticals, Inc.

Watch the RESPIMAT video and test your knowledge with a short multiple-choice quiz. When you get all the answers right, you’ll receive a certificate naming you a RESPIMAT T.O.P. Performer. Why not check it out today?

Pharmacy Times Strategic Alliance

Pharmacist Education
Clinical features with downloadable PDFs

Next-Generation Pharmacist® Awards

3rd Annual Convenient Healthcare and Pharmacy Collaborative Conference

Personalize the information you receive by selecting targeted content and special offers.