Researchers have found that an inhalant might serve as a means of applying iloprost therapy to patients with pulmonary arterial hypertension (PAH). The iloprost inhalation solution was approved by the FDA in December 2004. The findings were from a follow-up study investigating the long-term safety, dosing, and clinical benefits of this therapy over a 2-year period. The study, involving 52 PAH patients, showed that inhaled iloprost was effective for the long-term treatment of PAH in affected patients, with 2-year data suggesting sustained benefit. Patients with primary or idiopathic PAH had a 2-year survival rate of 91%, compared with a predicted survival of 63% for similar yet untreated patients. This therapy, researchers claim, will provide physicians with a noninvasive treatment option when considering prostacyclin therapy for their PAH patients.
One study linked multiple pregnancies to an increased risk of developing atrial fibrillation later in life, and another investigated the association between premature delivery and cardiovascular disease.
Clinical features with downloadable PDFs