Cholesterol Is Associated with Progeria

MAY 01, 2005

Changes in cholesterol may speed up heart disease in patients with progeria. Because progeria is a genetic disease that accelerates the aging process, these patients are more at risk for cardiovascular problems. A study, reported in the Journal of Pediatrics (March 2005), found that decreased levels of high-density lipoprotein (HDL; "good") cholesterol might factor into early heart disease in these children.

The researchers also noted that adiponectin, a hormone that regulates the metabolism of fat and sugar, may be associated with the disease process. They examined the cholesterol levels in children with the disease and those without it. The results of the study showed that children with progeria had decreased levels of HDL cholesterol and adiponectin in their middle and later years, compared with children without the disease. The investigators hypothesized that low HDL and adiponectin may add to faster plaque formation.


Become a Respimat Top Performer 

Get to know RESPIMAT, the slow-moving mist inhaler from Boehringer Ingelheim Pharmaceuticals, Inc. 

Watch the RESPIMAT video and test your knowledge with a short multiple-choice quiz. When you get all the answers right, you’ll receive a certificate naming you a RESPIMAT T.O.P. Performer. Why not check it out today? 


Pharmacy Times Strategic Alliance

Pharmacist Education
Clinical features with downloadable PDFs

Next-Generation Pharmacist® Awards

3rd Annual Convenient Healthcare and Pharmacy Collaborative Conference

Personalize the information you receive by selecting targeted content and special offers.