A study, reported in Arthritis & Rheumatism (January 2005), identified a possible biomarker to predict osteoarthritis (OA). For the study, the researchers took blood samples from 753 Caucasian and African American men and women. The researchers discovered a strong link between high levels of hyaluronic acid and severe knee and hip arthritis. Hyaluronic acid is defined as a component of connective tissue that is widely distributed throughout the body and plays a major role in joint function.
The results of the study showed that hyaluronic acid levels were higher in individuals with more severe OA and with OA in >1 joint. The study, however, did not find any independent connections between high hyaluronic acid and other health problems seen in the OA patients (eg, hypertension, diabetes, and cancer).
One study linked multiple pregnancies to an increased risk of developing atrial fibrillation later in life, and another investigated the association between premature delivery and cardiovascular disease.
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