Cholesterol-lowering drugs (statins) may also help lower blood pressure to a moderate extent, according to the results from a 6- month University of California, San Diego study. The researchers based their findings on 1016 men and postmenopausal women without known heart disease whose low-density lipoprotein (LDL; "bad") cholesterol levels were high.
During the study, the participants were randomly assigned to take simvastatin, pravastatin, or placebo. Blood pressure was measured before, during, and after the trial. Reporting the results at the recent American Heart Association annual meeting, the researchers explained that blood pressure was greatly reduced to a similar degree with both statin drugs. The change was evident 1 month after treatment and disappeared by 2 months after the medications were stopped. Specifically, the reduction witnessed was about 7 points for both the upper and lower readings.
Although the study had limitations, researcher Beatrice A. Golomb, MD, PhD, said the findings "may help to explain stroke reduction with statins, since LDL cholesterol bears little relationship to stroke risk, while blood pressure is a potent risk factor."
The Oncology Care Pharmacist in Health-System Pharmacy
According to the National Cancer Institute, almost 40% of men and women will be given a diagnosis of some form of cancer in their lifetime.
News from the year's biggest meetings
Clinical features with downloadable PDFs