Memantine HCl/Donepezil Combo Improves Functioning

SEPTEMBER 01, 2004
Susan Farley

A phase 3, randomized, placebo-controlled clinical trial of the combination of memantine HCl (Namenda) and donepezil HCl (Aricept) showed that patients were able to maintain higher functional abilities, such as grooming and toileting, as well as showing improved behavioral symptoms, including irritability and agitation. The study of 404 patients treated with the memantine/donepezil combination demonstrated higher functioning, as measured by the Alzheimer's Disease Cooperative Study?Activities of Daily Living. This instrument assesses 19 activities of daily living, including personal care, communicating, simple domestic chores, maintaining autonomy, and making judgments and decisions. Patients taking the drug combination scored significantly higher in grooming, being left alone, and toileting, compared with those patients taking only donepezil.



SHARE THIS SHARE THIS
0

Conference Coverage from ASHP Summer 2017 

Four years after they first launched the Summer Meetings in Minneapolis, Minn., the ASHP 2017 Summer Meetings and Exhibition was in Minneapolis once again.  

 

Pharmacy Times Strategic Alliance
 

Pharmacist Education
Clinical features with downloadable PDFs


Next-Generation Pharmacist® Awards


3rd Annual Convenient Healthcare and Pharmacy Collaborative Conference


SIGN UP FOR THE PHARMACY TIMES NEWSLETTER
Personalize the information you receive by selecting targeted content and special offers.