Data from the INITIATE (INITiation of Insulin to reach A1c TargEt) study revealed that Novo Nordisk's NovoLog Mix 70/30 (70% insulin aspart protamine suspension and 30% insulin aspart injection [rDNA origin]), a dual-action insulin analog without neutral protamine Hagedorn, showed improved blood glucose lowering in patients with type 2 diabetes. The researchers found that NovoLog Mix 70/30 is more effective in helping patients who are starting insulin therapy to achieve control of their blood glucose levels, compared with insulin glargine.
The study examined insulin-na ïve patients whose blood glucose levels were not being controlled with oral diabetes medications (A1c levels >8%). After 28 weeks, 66% of patients taking NovoLog Mix 70/30 achieved levels of 7%, compared with 40% in the insulin glargine group. In fact, 42% of patients taking NovoLog Mix 70/30 reached an A1c of ≤6.5%, compared with 28% taking glargine. (The findings were presented at the annual meeting of the American Diabetes Association.)
One study linked multiple pregnancies to an increased risk of developing atrial fibrillation later in life, and another investigated the association between premature delivery and cardiovascular disease.
Clinical features with downloadable PDFs