Comorbid IBS Affects PPI Treatment for GERD

AUGUST 01, 2004

Patients with irritable bowel syndrome (IBS) frequently suffer from symptoms that are characteristic of gastroesophageal reflux disease (GERD), suggesting that comorbidity is not uncommon. It is not known, however, whether comorbid IBS in patients with GERD affects the efficacy of proton pump inhibitors (PPIs), which are typically used to treat patients with GERD.

A study conducted by William D. Chey, MD, and colleagues, presented at the 105th Annual Meeting of the American Gastroenterological Association and Digestive Disease Week (DDW), held from May 15 to 20, 2004, in New Orleans, La, examined the relationship between the presence of comorbid IBS and PPI efficacy in patients with GERD (n = 68). Results showed that patients with GERD and comorbid IBS have more severe GERD symptoms than do individuals with GERD alone. Also, patients with both GERD and IBS are more likely to experience residual GERD symptoms during PPI therapy than are those with GERD alone.



SHARE THIS SHARE THIS
0
 

In Seniors: Consider CMV Serostatus
When Recommending Flu Vaccine

Older people who have cytomegalovirus seem to have less robust responses to the trivalent influenza vaccine than those who do not have CMV.


 

 

Conference Coverage
News from the year's biggest meetings


Pharmacist Education
Clinical features with downloadable PDFs


 

SIGN UP FOR THE PHARMACY TIMES NEWSLETTER
Personalize the information you receive by selecting targeted content and special offers.