Fibromyalgia, a condition characterized by excessive somatic hyperalgesia, and irritable bowel syndrome (IBS), a prevalent gastrointestinal disorder characterized by abdominal pain/discomfort and altered bowel function, often occur together. Up to 32% of patients with fibromyalgia have IBS, and 81% report irregular bowel habits.
In the April 2004 issue of Annals of the Rheumatic Diseases, Mark Pimentel, MD, and colleagues reported the results of a study that examined the association between fibromyalgia and small intestinal bacterial overgrowth (SIBO), which has been linked to IBS. The double-blind study used the lactose breath test (LBT) to examine SIBO in patients with fibromyalgia (n = 42), patients with IBS (n = 111), and controls (n = 15). The results demonstrated that 100% of the patients with fibromyalgia and 84% of those with IBS had an abnormal LBT, compared with 15% of controls. The authors concluded that an abnormal LBT (indicative of SIBO) may be a common link between fibromyalgia and IBS.
One study linked multiple pregnancies to an increased risk of developing atrial fibrillation later in life, and another investigated the association between premature delivery and cardiovascular disease.
Clinical features with downloadable PDFs