Diabetes Treatment Raises Cholesterol Ratio

Published Online: Tuesday, July 1, 2003

A new study has found that the type 2 diabetes treatment rosiglitazone increased high-density lipoprotein (HDL, or "good") cholesterol levels and improved the ratio of total cholesterol to HDL cholesterol in patients with type 2 diabetes. Data from the study were presented recently at the Annual Scientific Session of the American College of Cardiology.

In the study?which analyzed the results of open-label extensions of 2 placebo-controlled, double-blind studies?a total of 269 patients were given 8 mg of rosiglitazone daily for 24 months. In all the patients, mean HDL cholesterol levels increased by 15%, with increases of 25% in patients with HDL cholesterol levels <40 mg/dL at baseline.The ratio of cholesterol to HDL cholesterol improved for all the patients, with an overall decrease from 5.06 to 4.7 over 2 years. In patients with a ratio >5, the mean ratio decreased from 6.25 to 5.6.



Latest Articles
This weekly video program provides our readers with an in-depth review of the latest news, product approvals, FDA rulings and more.
Chronic kidney disease incidence has grown faster than many of its common comorbidities such as diabetes and hypertension, and medications may be an underappreciated driver of this growth.
President Barack Obama’s fiscal year 2017 budget proposal calls for an additional $1.1 billion to combat the nation’s spiraling opioid epidemic.
Baxter International is voluntarily recalling intravenous solution due to leaking containers and the potential for particulate matter.
Latest Issues
$auto_registration$
VSEO N/A