Cholesterol Gets the 1-2 Punch

JULY 01, 2003

The latest research indicates that taking 2 different types of cholesterol-lowering drugs reduces cholesterol in the blood better than taking either drug independently. Participants who took both atorvastatin and ezetimibe showed a larger decrease in cholesterol with no additional side effects, compared with patients who took either drug alone, according to findings published recently in Circulation. Atorvastatin inhibits the liver?s natural production of cholesterol, whereas ezetimibe works by preventing the intestines from absorbing cholesterol.

The researchers gave 628 patients with high cholesterol 1 of 4 treatments: ezetimibe alone, atorvastatin alone, ezetimibe plus ator-vastatin, or a placebo drug. After 12 weeks, the researchers discovered that participants taking the combination of the 2 cholesterol drugs showed a 12% larger drop in levels of low-density lipoprotein ("bad") cholesterol, compared with patients taking only atorvastatin. Furthermore, the combined treatment reduced levels of triglycerides and C-reactive protein more successfully than did atorvastatin alone, the authors of the study said.



SHARE THIS SHARE THIS
0

Conference Coverage from ASHP Summer 2017 

Four years after they first launched the Summer Meetings in Minneapolis, Minn., the ASHP 2017 Summer Meetings and Exhibition was in Minneapolis once again.  

 

Pharmacy Times Strategic Alliance
 

Pharmacist Education
Clinical features with downloadable PDFs


Next-Generation Pharmacist® Awards


3rd Annual Convenient Healthcare and Pharmacy Collaborative Conference


SIGN UP FOR THE PHARMACY TIMES NEWSLETTER
Personalize the information you receive by selecting targeted content and special offers.