The use of topicalb-blockers for the treatment of glaucoma is associated with an increased risk of airways obstruction in elderly patients, according to a report in the British Medical Journal. Researchers matched people who had used topical b-blockers with unexposed people by age and sex. An estimated 55 patients would need to be treated to cause 1 case of airways obstruction each year.
Ophthalmologists, general practitioners, physicians, and pharmacists need to be aware of the possibility of airways obstruction in patients taking topicalb-blockers for glaucoma, the researchers noted. b-blockers should be discontinued immediately when a patient develops airways obstruction, and the ophthalmologist should be informed, the researchers added.
A repeat prescription that includes topicalb-blockers and drugs for asthma should automatically sound an alarm, the authors concluded.
One study linked multiple pregnancies to an increased risk of developing atrial fibrillation later in life, and another investigated the association between premature delivery and cardiovascular disease.
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