Naturally Occurring Carbohydrates May Cause Arthritis

SEPTEMBER 01, 2002

Glycosaminoglycans (GAGs) may cause rheumatoid arthritis, according to findings presented at the American Chemical Society?s national meeting, held in August in Boston, MA. GAGs are naturally present in joint cartilage, joint fluid, connective tissue, and skin. Researchers demonstrated that GAGs induced arthritic symptoms (including swelling, inflammation, and joint damage) in animal models as well as in human tissue taken from arthritis patients.

?This study shows that rheumatoid arthritis may result from the body?s mishandling of its own carbohydrates that, under normal circumstances, would not be interpreted as a threat,? said lead researcher Dr. Julia Ying Wang, assistant professor of medicine, Harvard Medical School, Boston. ?We found that inflammatory cells that accumulate in arthritic joints attach themselves directly to the GAGs. This accumulation of cells leads to painful inflammation and swelling in the affected tissue.?



SHARE THIS SHARE THIS
0

Conference Coverage

Check back here regularly for live conference coverage from the American Academy of Pain Medicine and the upcoming American Pharmacists Association Meeting and Expo. 


Pharmacy Times Strategic Alliance
 

Pharmacist Education
Clinical features with downloadable PDFs


Next-Generation Pharmacist® Awards


3rd Annual Convenient Healthcare and Pharmacy Collaborative Conference


SIGN UP FOR THE PHARMACY TIMES NEWSLETTER
Personalize the information you receive by selecting targeted content and special offers.