Migraines Linked to Major Depressive Disorder

Kate H. Gamble, Senior Editor
Published Online: Monday, November 28, 2011
Follow Pharmacy_Times:
Individuals who have migraines have a higher chance of experiencing major depressive episodes, according to research published online in the journal Headache. The study also found that those with major depressive episodes are at an increased risk of having migraines.

It is critical, therefore, that individuals who suffer from migraines learn about major depressive symptoms, and that those with clinical depression know about the signs and symptoms of migraines, said lead author Geeta Modgill, MsC, of the University of Calgary.

Previous population-based cross-sectional studies had indicated that there is likely a link between depression and migraine, a condition that affects more than 28 million adults in the United States and is more common in women. Longitudinal studies, however, had not demonstrated compellingly that the link works both ways.

In the study, Modgill and colleagues analyzed data from 15,254 individuals from the Canadian National Population Health Survey to determine whether major depressive episodes (MDEs) were linked to a higher migraine risk in the general population, and whether migraine might be associated with MDE risk.

Investigators found that overall, 15% of individuals had MDEs and 12% had bouts of migraine during the 12-year study period. They reported that migraine sufferers have a 60% higher risk of suffering from MDEs compared to those who never have migraines, and that individuals who experienced MDEs have a 40% higher chance of developing migraine compared to those without MDEs, according to an online article.

In both cases, adjustments were made for sex, age, and other chronic conditions. The investigators believe that certain factors such as childhood stress may impact how the brain subsequently responds to stress.

“The current study provides substantial evidence that migraine is associated with the later development of MDEs, but does not provide strong causal evidence of an association in the other direction,” they concluded. “Environmental factors such as childhood trauma and stress may shape the expression of this bidirectional relationship; however, the precise underlying mechanisms are not yet known.”

Related Articles
mscripts and Avella Specialty Pharmacy have recently completed analyzing data demonstrating the effectiveness of mobile pharmacy apps in helping HIV patients better manage their disease through improved medication adherence. Results from this analysis show that HIV patients using a mobile app which provides refill reminders, dosage reminders and other prescription management functionality are 2.9 times more likely to be adherent.
A community pharmacy can collaborate with a local hospital to provide quality medication education and adherence coaching.
Think, communicate, lead, implement, and advocate. These are the 5 core tenets that Fairleigh Dickinson University School of Pharmacy emphasizes for its pharmacy students.
Kentucky pharmacist Larry Fortenberry had always imagined what he would do in a robbery situation, and he believed that passive, obedient behavior would be the safest bet.
Latest Issues
  • photo
    Pharmacy Times
    photo
    Health-System Edition
    photo
    Directions in Pharmacy
    photo
    OTC Guide
    photo
    Generic Supplements
  • photo
    Pharmacy Careers
    photo
    Specialty Pharmacy Times
    photo
    Generic
$auto_registration$