Diabetes

In addition to improved efficacy, newer generations of anti-obesity medications have significantly improved safety concerns.

Expert Jennifer Clements discussed the evolving landscape of weight management medications, clinical considerations, and obstacles to use.

The oral medication activates an “anti-hunger” molecule which may prevent people from overeating.

A notable revision now includes a dual GIP and GLP-1 receptor agonist (tirzepatide) as an additional option for glycemic management, preferred over insulin.

This guide discusses the integration of continuous glucose monitoring (CGM) technology into clinical practice, emphasizing the role of pharmacists in selecting and optimizing CGM devices for patients.

GBS can cause transcriptional adaptations, which may increase risk of poor neonate outcomes.

CGM enhances diabetes management in pregnancy, improving outcomes.

Teplizumab is indicated to delay the onset of Stage 3 type 1 diabetes (T1D) in adults and pediatric patients 8 years of age and older with stage 2 T1D.

Promising data have emerged suggesting a significant weight loss benefit for patients using GLP-1 agonists and GLP-1/GIP dual agonists.

Continuous glucose monitoring (CGM) is a valuable tool in managing diabetes, offering real-time data on glucose levels throughout the day.

Diabetes is a known risk factor for cognitive decline and small vessel disease.

Vitamin D preserved insulin-producing cells and cell function, which can reduce complications in young patients.

The continuous glucose monitoring system will be available for purchase online and without a prescription starting in summer 2024.

In the study, investigators found superior kidney outcomes with injectable semaglutide (Ozempic) for individuals with type 2 diabetes and chronic kidney disease.

In some instances, metabolites can predict risk in patients who still have normal glucose biomarkers.

Nearly 60% of patients who regained all the weight stayed in remission at 5 years post-surgery, according to study results.

Continued doses of denosumab reduced the incidence of diabetes by more than 1000 patients compared to an initial dose alone.

In a projective model, tirzepatide saved patients more than $15,000 per quality-adjusted life-year.

Mouthwash that contains chlorhexidine gluconate was especially effective at improving hyperglycemic status in younger patients with diabetes.

This agent can prevent the depletion of heparan sulphate in the endothelial glycocalyx layer of endothelial cells, ultimately protecting against vision loss and renal failure caused by diabetes.

Providing continuity of care with the involvement of midwives also appeared to reduce inequities in care for multi-ethnic patients.

By involving pharmacists, patients can see improved medication adherence, improved outcomes, and, as a result, reduced health care costs

There are 2 features of weight loss interventions which are most likely to improve weight loss outcomes—having access to professional health coaches and social support from other users.

Defective RNA editing in cells in the pancreas may spur the body to initiate an inflammatory attack against its own cells.

Inadequate levels of zinc, vitamin D, vitamin E, and vitamin B were also associated with risk of diabetes or diabetes-related complications.

These patients may have a similar genetic susceptibility for type 2 diabetes.

These patients may have a similar genetic susceptibility for type 2 diabetes, although they have an individual risk for GDM independent of the risk of type 2 diabetes.

This combination regimen, which was compared to once-daily insulin glargine U100 with insulin aspart, had also demonstrated a safe and well-tolerated profile with mild AEs.

Most important of all, we gained a new level of empathy and understanding for patients diagnosed with diabetes whose diagnosis requires that they are constantly mindful and attentive to the balance of diet, exercise, and lifestyle in their day-to-day lives.