Closed-System Drug Transfer Devices Evaluated in Study

FEBRUARY 06, 2019
Amid concern over test protocols for closed-system drug transfer devices (CSTDs), an independent study has examined the effectiveness of various CSTD models.1

CSTDs, when designed and used appropriately, offer enhanced protection against potentially hazardous exposures to health care workers during the compounding and administration of hazardous drugs.2

The study, conducted by researchers at the Centre Hospitalier Régional in France, first performed a total of 21 usability tests on 7 CSTDs: ChemoClave, ChemoLock, Equashield, Phaseal, Qimono, Tevadaptor, and Viashield.1

The researchers then conducted a leak test on the 7 devices using fluorescein solution 0.05%. Although spots of fluorescein were not found on the researchers’ gloves or in the working area when using any of the CSTDs, they were found on 4 of the devices (ChemoClave, Phaseal, Qimono, and Viashield) themselves.1

Finally, researchers performed an additional 10 leak tests on each of the 3 devices (ChemoLock, Equashield, and Tevadaptor) that were not found to have leaked during the previous testing phase. Of the 3 CSTDs, only Equashield was found to have passed all the tests positively.1

“It is possible to secure hazardous drugs preparations with CSTD but all devices are not equivalent,” the study authors concluded.1 “These tests lead to choose 1 device rather than another to secure the preparation in the care units.”

The study results were presented European Conference of Oncology Pharmacy in Nantes, France.1

According to the CDC, the United States' National Institute for Occupational Safety and Health recommends health care workers use a CSTD throughout the hazardous drug-handling chain, from pharmaceutical compounding to patient dose administration.2 


Reference
  1. Masson F, Henry C, Lanher P, Noirez V, Rondelot G. Closed-system drug transfer devices: comparative study of different models. Presented at: European Conference of Oncology Pharmacy. October 25-27, 2018. Nantes, France. Accessed February 5, 2019.
  2. National Institute for Occupational Safety and Health. Closed System Drug-Transfer Device (CSTD) Research Overview. NIOSH. Published January 29, 2019. Accessed February 6, 2019.


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