Acid Reflux: More Than a Nuisance

Published Online: Friday, May 30, 2014
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Nurse practitioner and digestive diseases expert Jan Seliga answers questions about acid reflux, which is frequently dismissed as a nuisance, but can lead to serious damage to the stomach and esophagus if not properly treated.

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A new Mayo Clinic study published in Microbiome shows that patients with acid reflux who regularly receive proton pump inhibitors have less diverse gut bacteria, which heightens their risk for bone fractures, vitamin deficiencies, and infections such as Clostridium difficile and pneumonia.
Patients on 20-mg maintenance doses of esomeprazole reported no more than mild symptom severity.
As a result of confusing sensations of breathlessness with asthma symptoms, overweight and obese children tend to report poorer asthma control and overuse rescue medications.
As nearly one-third of patients with gastroesophageal reflux disease are partial responders to proton pump inhibitors (PPIs), health care professionals could benefit from reliable methods that predict who will respond to PPIs and who will not.
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