Cipro Shown More Effective Than Augmentin

Susan Farley
Published Online: Friday, April 1, 2005

A recent report in the Journal of the American Medical Association has shown that ciprofloxacin (Cipro) more effectively treats bladder infections than amoxicillin-clavulanate (Augmentin). Researchers randomly assigned 370 women with cystitis to receive a 3-day course of either Cipro or Augmentin. The infection was cured in 77% of the women in the Cipro group, compared with 58% of women in the Augmentin group. Even after the researchers analyzed the women infected with bacteria susceptible to amoxicillin-clavulanate, they still found ciprofloxacin had a higher cure rate, due to its eradication of Escherichia coli bacteria from the vagina. When tested for vaginal E coli at the 2-week follow-up, 45% of the Augmentin group had E coli compared with 10% of the Cipro group. These results led the investigators to conclude that Augmentin should only be used as a treatment for cystitis when other first-and second-line antibiotics are not possible.

Ms. Farley is a freelance medical writer based in Wakefield, RI.

Latest Articles
A pharmacy robber not only left his fingerprints behind at a pharmacy—he also dropped his wallet containing his identification as he made his escape.
Janssen Research and Development LLC has submitted a new drug application to the FDA for canagliflozin and metformin hydrochloride extended release (Invokamet XR).
Treating chronic pulmonary obstructive disease with both inhaled corticosteroids and long-acting bronchodilators remains controversial, but new evidence suggests that this controller combination could reduce mortality risk.
Beverly Schaefer, RPh, of Katterman's Sand Point Pharmacy in Seattle, Washington, shares some fun tips on how to encourage patients who travel to come to your pharmacy for supplies.
Latest Issues