Pharmacy Times

Hypertension Affects Optimum Post-stroke BP


The optimum poststroke blood pressure (BP) appears to be higher in patients with a history of hypertension than those without, as shown in a study conducted at the University of the Ryukyus, Okinawa, Japan.

The study team admitted, however, that "the association between BP after stroke onset and outcome has not been fully understood."

The team examined data on 1004 patients with ischemic stroke and 1097 with hemorrhagic stroke who were admitted to the hospital on the day of stroke onset.

The analysis showed a "u-shaped" relationship between admission BP levels and the 30-day mortality rate in patients with ischemic stroke, with intermediate BP levels associated with a lower mortality rate, and both high and low BP levels associated with a higher mortality rate. In patients with hemorrhagic stroke, only elevated BP was a predictor of poor prognosis.

The researchers concluded that the association between BP level and early prognosis after acute stroke depends not only on the type of stroke, but on the absence or presence of previous hypertension as well.