Too much acetaminophen may lead to a higher risk of asthma and chronic obstructive pulmonary disease (COPD), reported researchers in the American Journal of Respiratory and Critical Care Medicine (May 1, 2005). Using data from the Third National Health and Nutrition Survey, the investigators learned that the frequency of asthma was 6.9% and the frequency of COPD was 11.8%.
The results of their study also indicated that 2.8% of the >13,000 participants had both respiratory diseases. Of this group, ~4% used acetaminophen daily, compared with 8.2% who used aspirin and 2.5% who used ibuprofen. The researchers also pointed out that neither aspirin nor ibuprofen use was associated with the prevalence of either asthma or COPD.