Yvette C. Terrie, BSPharm, RPh
The elderly are more susceptible to problems with drug therapy, and pharmacists are pivotal in identifying possible drug interactions, contraindications, and incidences of polypharmacy.
Ms. Terrie is a clinical pharmacy writer
based in Haymarket, Virginia.
Results from a survey conducted
by the National Council for
Patient Education reported that
only 37% of patients who use nonprescription
drugs consult the pharmacist to
ensure proper selection and use.1 In
addition, many patients taking prescription
drugs also concurrently use nonprescription
drugs without first consulting
their physicians or pharmacists. These
individuals may not be aware of possible
therapeutic duplications, contraindications,
or drug interactions when some
nonprescription and prescription drugs
are used concurrently.
The elderly become more susceptible
to problems with drug therapy because
aging alters both pharmacokinetics and
pharmacodynamics, which impacts the
selection, dosage, and dosing interval of
many pharmacologic agents.2,3 Pharmacists
are pivotal in identifying possible
drug interactions, contraindications, and
incidences of polypharmacy.
Many Conditions, Various Medications
Individuals aged 65 and older account
for more than 12% of the population in
the United States, and this percentage is
expected to double by the year 2030.4
Because many seniors have multiple
chronic medical conditions, they are
most likely to take various medications,
including both prescription and nonprescription
drugs; therefore, the probability
of adverse effects increases, including
potential drug interactions and contraindications.
It is estimated that the elderly account
for 40% of the nonprescription drugs
(including nutritional supplements) sold
in the United States.4,5 On average, individuals
aged 65 and older take an estimated
1.8 nonprescription products
daily. Nonprescription drug use among
the elderly is most prevalent in the
Midwest among Caucasians and
women.2 Results from 1 study show that
women aged 65 and older take more
nonprescription drugs than men, using
an average of 3.8 nonprescription drugs.2
Analgesics, laxatives, and nutritional supplements
are the most commonly used
nonprescription drugs by the elderly.2
Examples of the most commonly
known nonprescription drugs responsible
for interactions among the elderly
include nonsteroidal anti-inflammatory
drugs, antihistamines, and antacids.2 The
use of these drugs, such as nasal and
oral decongestants, may exacerbate
some preexisting medical conditions.
Also, some in the elderly population
appear to be more sensitive to certain
classes of drugs, such as anticholinergic
drugs.2
Other medication problems affecting
the elderly include dosing considerations
due to hepatic or renal impairments,
which may require a dosing decrease or
increase in dosing intervals.2,3 Some seniors
also may have difficulty swallowing
certain dosage forms or have issues with
dexterity due to conditions such as
arthritis. Pharmacists can assist patients
by making recommendations, such as a
liquid or chewable dosage form, if applicable,
or easy-to-open containers to suit
their individual needs.
Benefits of Counseling
Although counseling every patient
about nonprescription drug use is not a
realistic option in the daily duties of a
pharmacist, when a patient does seek
advice regarding a nonprescription product,
pharmacists should seize every
opportunity to ensure that the patient is
thoroughly counseled on its proper use,
as well as determine the appropriateness
of therapy. Pharmacists also should
find out if the request for a nonprescription
product is to treat a side effect of
another medication.2 Particularly among
the elderly, when a patient is receiving a
prescription medication, pharmacists
should inform him or her about possible
drug interactions and contraindications
with any applicable nonprescription
drugs when warranted.
Patients also should be reminded to
always consult their primary health care
provider before taking any nonprescription
drugs—including nutritional supplements and herbal medications—and
when in doubt, to ask their health care
provider. In addition, seniors are more
likely to see several health care providers
due to multiple medical conditions, so it
is imperative that they provide each of
them with an updated, comprehensive
list of their medications. This list should
include prescription and nonprescription
drugs, as well as nutritional and herbal
supplements, and be brought to each
doctor's visit. Furthermore, encouraging
the use of a single pharmacy also can
minimize possible drug interactions and
medication duplications. See Table for
additional reminders.
As more and more of the elderly population
become proactive about their
health, it is important to empower them
with necessary information about their
drug therapy so that they make smart
choices to improve their quality of life.
Table |
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References
- National Council of Patient Information and Education. Uses and Attitudes About Taking Over the Counter Medicines: Findings of a 2003 National Opinion Survey. www.bemedwise.org/survey/survey.htm.
- Isetts, B, Brown, L. Patient Assessment and Consultation. In: Berardi R, Kroon L, Newton G, et al, eds. Handbook of Nonprescription Drugs. 15th Edition. Washington, DC: American Pharmacists Association; 2006:29-30.
- Basics of Geriatric Care: Clinical Pharmacology. In: Beers, M, ed. The Merck Manual of Geriatrics. Rahway, NJ: Merck Publishing; 2000:Chapter 6.
- Lam, A, Bradley, G. Use of Self Prescribed Nonprescription Medications and Dietary Supplements Among Assisted Living Facility Residents. Medscape Web site. www.medscape.com/viewarticle/549257.
- Conroy, M. Polypharmacy: Pandora's Medicine Chest? Geriatric Times. 2000. www.cmellc.com/geriatrictimes/g001028.html.