A recent report from London indicated
that urinary tract and respiratory infections
increase the risk of deep vein
thrombosis (DVT) and pulmonary embolus
(PE). Data from more than 10,000
episodes of thromboembolic events
(TEs) were analyzed in the study. In the 2
weeks following a urinary tract infection,
the risk of TEs more than doubled. The
risk did not return to normal levels for
more than a year. Respiratory infections
also were associated with an increased
risk of DVT, but the evidence regarding
PE was less clear.
Infections have long been suspected
as a link to cardiovascular problems
involving the arteries. The role of infectious
processes as a risk for venous
events, however, has not been clearly
defined. The mechanism of the increased
risk for TEs in the setting of an
acute infection is unknown.
Dr. Garrett is a clinical pharmacist practitioner
at Cornerstone Health Care in High
Point, NC.