Pfizer Inc (New York, NY) has
received FDA approval for the intravenous
antifungal Eraxis for the treatment
of candidemia, a potentially life-threatening
bloodstream infection, and
for the treatment of 2 other Candida
infections, peritonitis and intra-abdominal
abscesses. The product also is
approved for the treatment of esophageal
candidiasis. The recommended
dose for candidemia and other Candida
infections is a single 200-mg loading
dose of Eraxis on day 1, followed by a
100-mg daily dose thereafter. The recommended
dose for esophageal candidiasis
is a single 100-mg loading dose of Eraxis
on day 1, followed by a 50-mg daily dose
thereafter. Eraxis is available in 50-mg
single-use vials of sterile, lyophilized, preservative-free powder. The companion
single-use diluent vials contain 15 mL of
20% (w/w) dehydrated alcohol in water
for injection. For more information, visit
www.eraxisrx.com, or call 800-438-1985.